Sihao GAO (高思豪)
MD/PhD Student @PUMCH Pediatrics
Fields of interest
- Pediatric Rheumatology | Clinical Immunology | Medical Genetics
- Inborn Errors of Immunity | Autoinflammation
- Data Science | Clinical Epidemiology | Causal inference
Contact
- Email: sihao.gao@gmail.com
- Twitter: @SihaoGao
- ORCID: 0000-0001-8839-2982
- Google Scholar: https://scholar.google.com/citations?user=cg5EzYcAAAAJ
Publications
SCI Journals
First-authored
- Zhang Y*, Shen T*, Gao S*, Yan J, Shi J, Tang X, Wang M, Yang J, Yu H, Mao H, Shuai L, Li Y, Cao Y, Li X, Wang Y, Liu Q, Song H#, Wu X#. Validation and optimization of classification criteria for childhood-onset systemic lupus erythematosus in a multi-center Chinese cohort. Front Immunol. 2025;16:1611349. Published 2025 Jul 17. doi:10.3389/fimmu.2025.1611349
- Gao S*, Yu Z*, Ma X*, Sun J*, Ren A, Gao S, Gong M, Zhou X#, Ma M#, Song H#. Childhood-onset systemic lupus erythematosus in China, 2016–21: a nationwide study. The Lancet Child & Adolescent Health. 2024;8(10):762-772. doi:10.1016/S2352-4642(24)00172-X
- Gao SH, Gong MC, Song HM. Acute severe hepatitis of unknown origin in children: considerations from the perspective of immunology. World J Pediatr. 2022;18(8):529-532. doi:10.1007/s12519-022-00580-y
Co-authored
- Zhang C, Gao S, Sun Z, Wang T, Song H. The clinical phenotypes and therapeutic strategies for stiff skin syndrome: a case series with literature review. Orphanet J Rare Dis. 2025;20(1):318. Published 2025 Jun 23. doi:10.1186/s13023-025-03748-7
- Zhang C, Wang C, Gao S, Ma M, Wang W, Zhang T, Zhang Y, Tang X, Li Z, Sun Z, Wang L, Jin H, Zeng X, Song H. Application of the Scleroderma Clinical Trials Consortium Damage Index in patients with juvenile systemic sclerosis. Pediatr Rheumatol Online J. 2025;23(1):53. Published 2025 May 14. doi:10.1186/s12969-025-01110-6
- Wang Y, Su S, Ma M, Weng R, Zhang Z, Liu D, Yan X, Wang J, Wang Y, Zhang W, Yang S, Zhang H, Zhao D, Lu M, Li X, Zhu J, Zhang W, Yu H, Zhang D, Huang Y, Nong G, Cai X, Mao H, Sun F, Wu X, Rong Z, Zhang J, Li Z, Jiang X, Li X, Liu X, Li C, Sun L, Gao S, Yang J, Song H, Tang X; Chinese Alliance of Pediatric Rheumatic and Immunologic Diseases. Clinical characteristics and outcomes of COVID-19 in pediatric patients with rheumatic diseases. Pediatr Res. 2025;97(6):2045-2055. doi:10.1038/s41390-024-03561-1
- Zhang TY, Wang W, Gao SH, Yu ZX, Wang W, Zhou Y, Wang CY, Jian S, Wang L, Gou LJ, Li J, Ma MS, Song HM. LASSO-derived nomogram for early identification of pediatric monogenic lupus. World J Pediatr. 2024;20(11):1155-1167. doi:10.1007/s12519-024-00817-y
- Zhang C, Yu Z, Gao S, Ma M, Gou L, Wang C, Wang L, Li J, Zhong L, Zhou Y, Wang W, Song H. Efficacy and safety of thalidomide in children with monogenic autoinflammatory diseases: a single-center, real-world-evidence study. Pediatr Rheumatol. 2023;21(1):124. doi:10.1186/s12969-023-00881-0
- Wang W, Wang W, Peng S, Gao S, Quan M, Gou L, Wang C, Sun Z, Li Z, Lian D, Song H. Tocilizumab reduces the unmanageable inflammatory reaction of a patient with Aicardi-Goutières syndrome type 7 during treatment with ruxolitinib. Pediatr Rheumatol. 2023;21(1):117. doi:10.1186/s12969-023-00899-4
- Zhang T, Yu Z, Gao S, Zhang Y, Wang C, Jian S, Wang L, Gou L, Li J, Ma M, Song H. Clinical phenotypes and prognosis of cytomegalovirus infection in the pediatric systemic lupus erythematosus: a longitudinal analysis. Pediatr Rheumatol Online J. 2023;21(1):25. doi:10.1186/s12969-023-00807-w
- Zhang T, Yu Z, Gao S, Wang L, Song H. Systemic Lupus Erythematosus in Shwachman-Diamond Syndrome: a Novel Phenotype. J Clin Immunol. 2023;43(3):550-553. doi:10.1007/s10875-022-01425-z
- Wang W, Gao SH, Wei M, Zhong LQ, Liu W, Jian S, Xiao J, Zhang CH, Zhang JG, Zeng XF, Xia WB, Qiu ZQ, Song HM. Unique mutation spectrum of progressive pseudorheumatoid dysplasia in the Chinese population: a retrospective genotype–phenotype analysis of 105 patients. World J Pediatr. 2023;19(7):674-686. doi:10.1007/s12519-022-00674-7
- Wang T, Xue Y, Li Y, Gao S, Peng L, Zhao Y, Yu S. DJ-1 Protein Inhibits Apoptosis in Cerebral Ischemia by Regulating the Notch1 and Nuclear Factor Erythroid2-Related Factor 2 Signaling Pathways. Neuroscience. 2022;504:33-46. doi:10.1016/j.neuroscience.2022.09.016
Chinese Journals
First-authored
- 高思豪,宋红梅.关注系统性自身炎症性疾病的研究进展[J].中国实用儿科杂志,2024,39(6):422-424. doi:10.19538/j.ek2024060604.
- 高思豪,宋红梅.系统性自身炎症性疾病治疗进展[J].中国实用儿科杂志,2024,39(6):425-432. doi:10.19538/j.ek2024060605.
- 高思豪, 宋红梅. 快速进展的自身炎症性疾病[J]. 罕见病研究,2022,1(3):238-244. doi:10.12376/j.issn.2097-0501.2022.03.003
Co-authored
- 施勇旺, 高思豪, 徐萌, 丁娟, 何艳燕, 张志文, 任新瑜, 王晓月, 杨思睿, 宋红梅. STAT4基因变异和局限性硬皮病表现的自身炎症性疾病1例[J]. 中华儿科杂志,2025,63(07):802-804. doi:10.3760/cma.j.cn112140-20250205-00088
- 于仲勋, 高思豪, 马明圣.Ⅰ型干扰素病研究进展[J].中国实用儿科杂志,2024,39(06):444-448. doi:10.19538/j.ek2024060608.
- 王薇, 张越伦, 高思豪, 宋红梅. 《中国自身炎症性疾病基因诊断指南》计划书[J]. 协和医学杂志,2023,14(2):241-246. doi:10.12290/xhyxzz.2023-0077
- 王薇, 李小琳, 李文道, 欧俊斌, 高思豪, 张彩慧, 刘玉玲, 孙智才, 马明圣, 宋红梅. DNASE1L3基因纯合缺失变异致单基因狼疮一家系并文献复习[J]. 中华儿科杂志,2022,60(12):1276-1281. doi:10.3760/cma.j.cn112140-20220926-00839
Conference presentations
- 高思豪, 王薇, 马明圣, 宋红梅. 中国儿童免疫性疾病多中心研究网络平台的建立[C]. 中华医学会第二十七次全国儿科学术大会. (2022/12/18)
- Gao S, Yu Z, Ma X, Sun J, Ren A, Gao S, Gong M, Zhou X, Ma M, Song H. Landscape of childhood-onset systemic lupus erythematosus in China, 2016-2021. 26th Asia-Pacific League of Associations for Rheumatology Congress (APLAR 2024). (2024/08/24)
- 高思豪, 于仲勋, 马旭东, 孙佳璐, 任爱国, 高嗣法, 弓孟春, 周翔, 马明圣, 宋红梅. 2016-2021年中国儿童系统性红斑狼疮的发病现况:一项横断面研究[C]. 中华医学会第二十九次全国儿科学术大会. (2024/10/11)
- Sihao Gao, Yongwang Shi, Xu Meng, Juan Ding, Zhuo Li, Jingjing Jiang, Yanyan He, Sirui Yang, Hongmei Song. Panniculitis and IgA deficiency in a 6-year-old girl with polyarthritis. 6th Asia Pacific Society for Immunodeficiencies Congress (APSID 2025). (2025/04/11)
Research Projects
- National Key R&D Program of China – Precision Diagnosis and Treatment for Pediatric Immune Diseases (Participating, 2021-2024)
Memberships
- Asia Pacific Society for Immunodeficiencies (Junior member, 2023-)
- American College of Rheumatology (Student/Resident member, 2023-)
Education
- 2021-2026 Peking Union Medical College Hospital, MD/PhD Candidate in Pediatrics.
- 2016-2021 Chongqing Medical University, Bachelor of Medicine in Pediatrics. (Honors)